Papers/PMID:41811641
Propranolol mitigates sleep apnea-related cardiac responses during CPAP withdrawal: a randomized placebo-controlled cross-over clinical study.
Sleep & breathing = Schlaf & Atmung2026The record
1 finding · 1 compound · 1 endpoint
What it reported
How to read these marksWhat moved
1 finding
propranolol — decreases diastolic blood pressure (setting unspecified)
Evidence strength: moderate.Finding“Propranolol caused a trend in reduction of systolic morning blood pressure from 131 to 125 mm Hg (mean difference, 6.1 [−11.5, 28]) and significantly reduced diastolic blood pressure from 80 to 76 mmHg (mean difference, 4.3 [−10, 17.5]).”
Quoted verbatim from Propranolol mitigates sleep apnea-related cardiac responses during CPAP withdrawal: a randomized placebo-controlled cross-over clinical study.. - Study
- crossover
- Dose
- propranolol long-acting 80 mg in the evening, versus placebo
- Population
- Adults with obstructive sleep apnea (mean age 51, BMI 33.8) undergoing a 3-night CPAP withdrawal protocol; morning measurement after the night
Propranolol mitigates sleep apnea-related cardiac responses during CPAP withdrawal: a randomized placebo-controlled cross-over clinical study.2026PMID:4181164110.1007/s11325-026-03645-8An author is affiliated with a producerPermalink