Papers/PMID:41534622
Arginine therapy in sickle cell disease: A systematic review and meta-analysis of clinical outcomes.
Clinical nutrition ESPEN2026The record
1 finding drawn from this paper, on 1 compound across 1 endpoint, 1 of them null.
What it reported
How to read these marksEvery finding here is a null result.
What did not
1 finding
L-arginine — no detected effect on arginine-to-ornithine ratio
PreliminaryGrade D, Preliminary. Non-human or in vitro only.FindingNull result“Pharmacodynamic analysis confirmed increased plasma arginine levels but showed no significant change in the arginine-to-ornithine ratio.”
Quoted verbatim from Arginine therapy in sickle cell disease: A systematic review and meta-analysis of clinical outcomes.. - Study
- meta-analysis
- Population
- Sickle cell disease patients with vaso-occlusive crises; meta-analysis of 8 RCTs (n=830) of L-arginine vs placebo or standard care; pharmacodynamic sub-analysis
Arginine therapy in sickle cell disease: A systematic review and meta-analysis of clinical outcomes.2026PMID:41534622