L-arginine/Finding
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No detected effect on arginine-to-ornithine ratio
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.FindingNull result“Pharmacodynamic analysis confirmed increased plasma arginine levels but showed no significant change in the arginine-to-ornithine ratio.”
Quoted verbatim from Arginine therapy in sickle cell disease: A systematic review and meta-analysis of clinical outcomes.. - Study
- meta-analysis
- Population
- Sickle cell disease patients with vaso-occlusive crises; meta-analysis of 8 RCTs (n=830) of L-arginine vs placebo or standard care; pharmacodynamic sub-analysis
Arginine therapy in sickle cell disease: A systematic review and meta-analysis of clinical outcomes.2026PMID:41534622Permalink
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- Everything the graph holds on L-arginine
- Every compound studied against Arginine-to-ornithine ratio
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To cite this finding: https://catalystproject.ai/e/01M2A329V49FQS96E3C00BGC6Z