Papers/PMID:41184785
Thiamine use and short-term prognosis in critical cerebrovascular disease: a propensity score matched retrospective analysis from the MIMIC-IV database.
BMC neurology2025The record
1 finding · 1 compound · 1 endpoint
What it reported
How to read these marksWhat moved
1 finding
thiamine — decreases all-cause mortality
LimitedEvidence strength: limited. Human evidence with several recorded weaknesses, or a design that tops out at limited.Findingreplicated ×2“With 1,585 matched pairs post-PSM, thiamine administration showed a significant association with decreased mortality at 7 days (HR = 0.68, 95%CI: 0.53-0.89, P = 0.004), 14 days (HR = 0.78, 95%CI: 0.64-0.96, P = 0.016), and 28 days (HR = 0.82, 95%CI: 0.69-0.98, P = 0.028) compared with non-thiamine use after adjustment.”
Quoted verbatim from Thiamine use and short-term prognosis in critical cerebrovascular disease: a propensity score matched retrospective analysis from the MIMIC-IV database.. - Study
- cohort
- Duration
- 4 weeks
- Population
- Critically ill patients with cerebrovascular disease in the MIMIC-IV database, propensity-score-matched thiamine users and non-users (1,585 matched pairs); 28-day all-cause mortality shown
Effect 0.82 hazard ratio, 95% CI 0.69 to 0.98
Thiamine use and short-term prognosis in critical cerebrovascular disease: a propensity score matched retrospective analysis from the MIMIC-IV database.2025PMID:41184785Permalink