Papers/PMID:41176956
Intraoperative methylene blue infusion reduces postoperative delirium in patients undergoing pancreatic surgery: A randomized controlled clinical trial.
Journal of clinical anesthesia2025The record
1 finding · 1 compound · 1 endpoint
What it reported
How to read these marksWhat moved
1 finding
methylene blue — decreases incidence of postoperative delirium
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Finding“A total of 55 patients (17.5%) experienced POD, with a lower POD incidence in the methylene blue group than in the control group (11.5% vs. 23.6%, p = 0.005).”
Quoted verbatim from Intraoperative methylene blue infusion reduces postoperative delirium in patients undergoing pancreatic surgery: A randomized controlled clinical trial.. - Study
- RCT
- Dose
- methylene blue 2 mg/kg IV within 60 min after anesthetic induction, followed by 1 mg/kg IV within 30 min before end of surgery
- Population
- adult patients undergoing pancreatic surgery
Intraoperative methylene blue infusion reduces postoperative delirium in patients undergoing pancreatic surgery: A randomized controlled clinical trial.2025PMID:41176956Permalink