Papers/PMID:40641714
Effect of Magnesium Supplements on Improving Glucose Control, Blood Pressure and Lipid Profile in Patients With Type 2 Diabetes Mellitus: A systematic review and meta-analysis.
Sultan Qaboos University medical journal2025The record
3 findings drawn from this paper, on 1 compound across 3 endpoints, 1 of them null.
What it reported
How to read these marksWhat moved
2 findings
magnesium(2+) — increases serum magnesium concentration
LikelyGrade B, Likely. Human evidence, limited replication or design limits.Findingreplicated ×1“The analysis indicated that Mg supplementation led to a significant increase in serum Mg concentrations (WMD = 0.69, 95% CI: 0.32 to 1.06; P < 0.01).”
Quoted verbatim from Effect of Magnesium Supplements on Improving Glucose Control, Blood Pressure and Lipid Profile in Patients With Type 2 Diabetes Mellitus: A systematic review and meta-analysis.. - Study
- meta-analysis
- Population
- adults with type 2 diabetes mellitus (T2DM); review pooled trials using oral and intravenous magnesium administration
Effect 0.69 mean difference, 95% CI 0.32 to 1.06
magnesium(2+) — decreases fasting blood glucose
LikelyGrade B, Likely. Human evidence, limited replication or design limits.Findingreplicated ×4“Overall, Mg supplementation was associated with a significant reduction in FBG levels compared to the control group in T2DM patients (WMD = –0.58, 95% CI: –0.87, –0.28; P < 0.01).”
Quoted verbatim from Effect of Magnesium Supplements on Improving Glucose Control, Blood Pressure and Lipid Profile in Patients With Type 2 Diabetes Mellitus: A systematic review and meta-analysis.. - Study
- meta-analysis
- Population
- adults with type 2 diabetes mellitus (T2DM); review pooled trials using oral and intravenous magnesium administration
Effect -0.58 mean difference, 95% CI -0.87 to -0.28
What did not
1 finding
magnesium(2+) — no detected effect on body mass index
LikelyGrade B, Likely. Human evidence, limited replication or design limits.FindingNull result“However, the analysis indicated that Mg supplementation did not significantly affect patients' BMI when compared to the control group (WMD = 0.03, 95% CI: –0.13 to 0.20; P = 0.68).”
Quoted verbatim from Effect of Magnesium Supplements on Improving Glucose Control, Blood Pressure and Lipid Profile in Patients With Type 2 Diabetes Mellitus: A systematic review and meta-analysis.. - Study
- meta-analysis
- Population
- adults with type 2 diabetes mellitus (T2DM); review pooled trials using oral and intravenous magnesium administration
Effect 0.03 mean difference, 95% CI -0.13 to 0.2