Papers/PMID:40450575
Prescribed in-hospital sodium intake for decompensated heart failure: A systematic review and meta-analysis.
Journal of hospital medicine2025The record
2 findings · 1 compound · 2 endpoints
What it reported
How to read these marksWhat moved
2 findings
sodium(1+) — decreases serum creatinine concentration
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Finding“Supplemental sodium with furosemide significantly decreased serum creatinine (pooled net mean difference [NMD]: -0.33 mg/dL, 95% confidence interval [CI]: [-0.50 to -0.17]), brain natriuretic peptide (pooled NMD: -62.84 pg/mL, 95% CI: [-103.61 to -22.08]), and weight (pooled NMD: -2.48 kg, 95% CI: [-4.31 to -0.66]).”
Quoted verbatim from Prescribed in-hospital sodium intake for decompensated heart failure: A systematic review and meta-analysis.. - Study
- meta-analysis
- Population
- Patients hospitalized for acute decompensated heart failure; supplemental sodium plus furosemide versus furosemide alone (furosemide in both arms); oral and intravenous sodium trials pooled
Effect -0.33 mean difference, 95% CI -0.5 to -0.17
Prescribed in-hospital sodium intake for decompensated heart failure: A systematic review and meta-analysis.2025PMID:40450575Permalink
sodium(1+) — decreases body mass
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Finding“Supplemental sodium with furosemide significantly decreased serum creatinine (pooled net mean difference [NMD]: -0.33 mg/dL, 95% confidence interval [CI]: [-0.50 to -0.17]), brain natriuretic peptide (pooled NMD: -62.84 pg/mL, 95% CI: [-103.61 to -22.08]), and weight (pooled NMD: -2.48 kg, 95% CI: [-4.31 to -0.66]).”
Quoted verbatim from Prescribed in-hospital sodium intake for decompensated heart failure: A systematic review and meta-analysis.. - Study
- meta-analysis
- Population
- Patients hospitalized for acute decompensated heart failure; supplemental sodium plus furosemide versus furosemide alone (furosemide in both arms); oral and intravenous sodium trials pooled
Effect -2.48 mean difference, 95% CI -4.31 to -0.66
Prescribed in-hospital sodium intake for decompensated heart failure: A systematic review and meta-analysis.2025PMID:40450575Permalink