Papers/PMID:39538180
L-arginine impact on inflammatory and cardiac markers in patients undergoing coronary artery bypass graft: a systematic review and meta-analysis of randomized controlled trials.
BMC cardiovascular disorders2024The record
2 findings drawn from this paper, on 1 compound across 2 endpoints, 1 of them null.
What it reported
How to read these marksWhat moved
1 finding
L-arginine — decreases interleukin-6 concentration
LikelyGrade B, Likely. Human evidence, limited replication or design limits.Finding“Our analysis also showed that L-arginine had a noticeable impact on decreasing interleukin-6 (IL-6) levels (WMD = -7.72 pg/ml; 95% CI: -15.05, -0.39).”
Quoted verbatim from L-arginine impact on inflammatory and cardiac markers in patients undergoing coronary artery bypass graft: a systematic review and meta-analysis of randomized controlled trials.. - Study
- meta-analysis
- Population
- adults undergoing coronary artery bypass grafting; overall pooled estimate
What did not
1 finding
L-arginine — no detected effect on tumour necrosis factor alpha concentration
LikelyGrade B, Likely. Human evidence, limited replication or design limits.FindingNull resultreplicated ×2“However, we found no considerable impact of L-arginine treatment on creatine phosphokinase-MB (CPK-MB), tumor necrosis factor-alpha (TNF-α), and troponin I compared to the placebo groups.”
Quoted verbatim from L-arginine impact on inflammatory and cardiac markers in patients undergoing coronary artery bypass graft: a systematic review and meta-analysis of randomized controlled trials.. - Study
- meta-analysis
- Population
- adults undergoing coronary artery bypass grafting; overall pooled estimate