Papers/PMID:38780173
Effects of potassium supplementation on plasma aldosterone: a systematic review and meta-analysis in humans.
Journal of hypertension2024The record
3 findings · 1 compound · 3 endpoints
What it reported
How to read these marksWhat moved
3 findings
K(+) — increases serum potassium concentration
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Findingreplicated ×2“Potassium supplementation caused a significant decrease in systolic BP (mean difference [95% CI] -3.69 mmHg [-4.91, -2.46], P < 0.001) and increase in serum potassium (+0.37 [0.23, 0.52] mmol/l, P < 0.001).”
Quoted verbatim from Effects of potassium supplementation on plasma aldosterone: a systematic review and meta-analysis in humans.. - Study
- meta-analysis
- Population
- Adults in clinical trials of potassium supplementation (meta-analysis)
Effects of potassium supplementation on plasma aldosterone: a systematic review and meta-analysis in humans.2024PMID:38780173Permalink
K(+) — decreases systolic blood pressure (setting unspecified)
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Findingreplicated ×4“Potassium supplementation caused a significant decrease in systolic BP (mean difference [95% CI] -3.69 mmHg [-4.91, -2.46], P < 0.001) and increase in serum potassium (+0.37 [0.23, 0.52] mmol/l, P < 0.001).”
Quoted verbatim from Effects of potassium supplementation on plasma aldosterone: a systematic review and meta-analysis in humans.. - Study
- meta-analysis
- Population
- Adults in the 18 of 36 potassium supplementation trials that also reported systolic blood pressure (meta-analysis)
Effect -3.69 mean difference, 95% CI -4.91 to -2.46
Effects of potassium supplementation on plasma aldosterone: a systematic review and meta-analysis in humans.2024PMID:38780173Permalink
K(+) — increases plasma aldosterone concentration
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Findingreplicated ×2“There was an increase in plasma aldosterone (standardized difference 0.426 [0.299, 0.553], P < 0.001) but not in plasma renin activity.”
Quoted verbatim from Effects of potassium supplementation on plasma aldosterone: a systematic review and meta-analysis in humans.. - Study
- meta-analysis
- Population
- Adults in 36 clinical trials of potassium supplementation (meta-analysis)
Effect 0.426 standardised mean difference, 95% CI 0.299 to 0.553
Effects of potassium supplementation on plasma aldosterone: a systematic review and meta-analysis in humans.2024PMID:38780173Permalink