Papers/PMID:38659018
Efficacy of selenium on patients undergoing cardiac surgery: a meta-analysis of randomized controlled trials.
Journal of cardiothoracic surgery2024The record
3 findings · 1 compound · 3 endpoints · 2 null
What it reported
How to read these marksWhat moved
1 finding
selenium atom — decreases C-reactive protein concentration
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.Finding“There was a significant reduction in postoperative CRP levels in the selenium intervention group compared to the control group (SMD -0.18; 95% CI: -0.34, -0.02; P = 0.03) after cardiac surgery.”
Quoted verbatim from Efficacy of selenium on patients undergoing cardiac surgery: a meta-analysis of randomized controlled trials.. - Study
- meta-analysis
- Population
- Adults after cardiac surgery in a pooled analysis of randomized trials of perioperative selenium versus control, CRP pooled across postoperative days 0, 2 and 3
Effect -0.18 standardised mean difference, 95% CI -0.34 to -0.02
Efficacy of selenium on patients undergoing cardiac surgery: a meta-analysis of randomized controlled trials.2024PMID:38659018Permalink
What did not
2 findings
selenium atom — no detected effect on intensive care unit length of stay
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.FindingNull result“The statistics demonstrated an insignificant association between the number of days spent in the ICU with postsurgical selenium intake (MD -0.01; 95% CI: -0.28, 0.25; P = 0.92).”
Quoted verbatim from Efficacy of selenium on patients undergoing cardiac surgery: a meta-analysis of randomized controlled trials.. - Study
- meta-analysis
- Population
- Adults after cardiac surgery in a pooled analysis of 7 randomized trials of perioperative selenium versus control
Effect -0.01 mean difference, 95% CI -0.28 to 0.25
Efficacy of selenium on patients undergoing cardiac surgery: a meta-analysis of randomized controlled trials.2024PMID:38659018Permalink
selenium atom — no detected effect on all-cause mortality
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.FindingNull result“The statistics of postoperative cardiac patients demonstrated an insignificant association of mortality with postoperative selenium intervention (RR 1.07; 95% CI: 0.84, 1.37; P = 0.57).”
Quoted verbatim from Efficacy of selenium on patients undergoing cardiac surgery: a meta-analysis of randomized controlled trials.. - Study
- meta-analysis
- Population
- Adults after cardiac surgery in a pooled analysis of 7 randomized trials of perioperative selenium versus control
Effect 1.07 risk ratio, 95% CI 0.84 to 1.37
Efficacy of selenium on patients undergoing cardiac surgery: a meta-analysis of randomized controlled trials.2024PMID:38659018Permalink