Papers/PMID:38128389
The efficacy of magnesium supplementation for gestational diabetes: A meta-analysis of randomized controlled trials.
European journal of obstetrics, gynecology, and reproductive biology2024The record
2 findings · 1 compound · 2 endpoints
What it reported
How to read these marksWhat moved
2 findings
magnesium(2+) — decreases HOMA-IR
Evidence strength: very limited.Findingreplicated ×4“Overall, compared with control intervention for gestational diabetes, magnesium supplementation was able to significantly decrease FPG (MD = -7.33 mg/dL; 95 % CI = -7.64 to -7.02 mg/dL; P < 0.00001) and HOMA-IR (MD = -0.99; 95 % CI = -1.76 to -0.22; P = 0.01), but resulted in no obvious impact on serum insulin (MD = -4.17 μIU/mL; 95 % CI = -8.49 to 0.14 μIU/mL; P = 0.06), preterm delivery (OR = 0.42; 95 % CI = 0.06 to 2.95; P = 0.38), macrosomia (OR = 0.34; 95 % CI = 0.08 to 1.35; P = 0.13) or BMI change (MD = -0.01 kg/m2; 95 % CI = -0.06 to 0.04 kg/m2; P = 0.63).”
Quoted verbatim from The efficacy of magnesium supplementation for gestational diabetes: A meta-analysis of randomized controlled trials.. - Study
- meta-analysis
- Population
- Women with gestational diabetes; five randomised controlled trials pooled
Effect -0.99 mean difference, 95% CI -1.76 to -0.22
The efficacy of magnesium supplementation for gestational diabetes: A meta-analysis of randomized controlled trials.2024PMID:3812838910.1016/j.ejogrb.2023.12.014Permalink
magnesium(2+) — decreases fasting blood glucose
Evidence strength: very limited.Findingreplicated ×11“Overall, compared with control intervention for gestational diabetes, magnesium supplementation was able to significantly decrease FPG (MD = -7.33 mg/dL; 95 % CI = -7.64 to -7.02 mg/dL; P < 0.00001) and HOMA-IR (MD = -0.99; 95 % CI = -1.76 to -0.22; P = 0.01), but resulted in no obvious impact on serum insulin (MD = -4.17 μIU/mL; 95 % CI = -8.49 to 0.14 μIU/mL; P = 0.06), preterm delivery (OR = 0.42; 95 % CI = 0.06 to 2.95; P = 0.38), macrosomia (OR = 0.34; 95 % CI = 0.08 to 1.35; P = 0.13) or BMI change (MD = -0.01 kg/m2; 95 % CI = -0.06 to 0.04 kg/m2; P = 0.63).”
Quoted verbatim from The efficacy of magnesium supplementation for gestational diabetes: A meta-analysis of randomized controlled trials.. - Study
- meta-analysis
- Population
- Women with gestational diabetes; five randomised controlled trials pooled
Effect -7.33 mean difference, 95% CI -7.64 to -7.02
The efficacy of magnesium supplementation for gestational diabetes: A meta-analysis of randomized controlled trials.2024PMID:3812838910.1016/j.ejogrb.2023.12.014Permalink