Papers/PMID:36849891
The effect of selenium therapy in critically ill patients: an umbrella review of systematic reviews and meta-analysis of randomized controlled trials.
European journal of medical research2023The record
1 finding · 1 compound · 1 endpoint
What it reported
How to read these marksWhat moved
1 finding
selenium atom — decreases all-cause mortality
Evidence strength: moderate.Findingreplicated ×7“Compared to a control group, selenium significantly decreased the incidence of mortality independent of the period of time (RR: 0.83, 95% CI 0.71, 0.98, P = 0.024 I2: 31.6%, GRADE = low certainty) (Additional file 1: Figure S1, Table S4 and Table 2).”
Quoted verbatim from The effect of selenium therapy in critically ill patients: an umbrella review of systematic reviews and meta-analysis of randomized controlled trials.. - Study
- meta-analysis
- Population
- critically ill adults; 16 randomised trials from five meta-analyses, intravenous selenium (selenite) against placebo, no treatment, standard care or low-dose selenium; mortality pooled irrespective of follow-up period
Effect 0.83 risk ratio, 95% CI 0.71 to 0.98
The effect of selenium therapy in critically ill patients: an umbrella review of systematic reviews and meta-analysis of randomized controlled trials.2023PMID:3684989110.1186/s40001-023-01075-wPermalink