PapersPMID:36113465
Structure and mechanism of human cystine exporter cystinosin.
- 01 · finding
- 1
- 02 · compound
- 1
- 03 · endpoint
- 1
- 04 · null
- 0
What it reported
How to read these marksWhat moved
1 finding
L-cystine — binds CTNS
Evidence strength: insufficient.Hypothesis“Here, we present structures of human cystinosin in lumen-open, cytosol-open, and cystine-bound states, which uncover the cystine recognition mechanism and capture the key conformational states of the transport cycle.”
Quoted verbatim from Structure and mechanism of human cystine exporter cystinosin.. - Study
- mechanistic · not in humans
- Population
- purified human cystinosin protein
Structure and mechanism of human cystine exporter cystinosin.2022PMID:3611346510.1016/j.cell.2022.08.020Permalink
Study record
Read under: L-cystine
- Design
- mechanistic study
- Species
- cells / none
- Population
- purified human cystinosin protein
- Participants
- not recorded
- Comparator
- not stated in the paper / within arm
- Duration
- not recorded
- Endpoints
- 1
- Record
- extracted
- Readings recorded
- 2