Papers/PMID:36008064
Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis.
BMJ open2022The record
2 findings · 1 compound · 2 endpoints · 2 null
What it reported
How to read these marksEvery finding here is a null result.
What did not
2 findings
thiamine — no detected effect on fasting blood glucose
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.FindingNull result“Pooled results from three trials demonstrated no statistically significant difference in the FBG level between those who received thiamine supplementation versus placebo after less than 3 months of follow-up (MD, −0.20 mmol/L; CI: −0.69 to 0.29).”
Quoted verbatim from Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis.. - Study
- meta-analysis
- Population
- Adults with type 2 diabetes; three pooled placebo-controlled trials; follow-up under 3 months
Effect -0.2 mean difference, 95% CI -0.69 to 0.29
Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis.2022PMID:36008064Permalink
thiamine — no detected effect on glycated haemoglobin (HbA1c)
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.FindingNull result“Two trials that investigated the effect of thiamine supplementation versus placebo on HbA1c levels demonstrated no statistically significant differences between the groups at less than 3-month follow-up period (mean difference, MD: −0.02%, 95% CI: −0.35 to 0.31).”
Quoted verbatim from Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis.. - Study
- meta-analysis
- Population
- Adults with type 2 diabetes; two pooled placebo-controlled trials; follow-up under 3 months
Effect -0.02 mean difference, 95% CI -0.35 to 0.31
Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis.2022PMID:36008064Permalink