Papers/PMID:35115662
Melatonergic agents influence the sleep-wake and circadian rhythms in healthy and psychiatric participants: a systematic review and meta-analysis of randomized controlled trials.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2022The record
1 finding · 1 compound · 1 endpoint
What it reported
How to read these marksWhat moved
1 finding
melatonin — decreases sleep onset latency
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.Findingreplicated ×10“The pooled SMD in healthy subjects showed that exogenous melatonin significantly decreased SOL compared to placebo.”
Quoted verbatim from Melatonergic agents influence the sleep-wake and circadian rhythms in healthy and psychiatric participants: a systematic review and meta-analysis of randomized controlled trials.. - Study
- meta-analysis
- Population
- Healthy adult participants; pooled RCTs of exogenous melatonin vs placebo, sleep onset latency by polysomnography or actigraphy
Melatonergic agents influence the sleep-wake and circadian rhythms in healthy and psychiatric participants: a systematic review and meta-analysis of randomized controlled trials.2022PMID:35115662Permalink