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Papers/PMID:34983595

Vitamin C for ≥ 5 days is associated with decreased hospital mortality in sepsis subgroups: a nationwide cohort study.

Critical care (London, England)2022The record

1 finding · 1 compound · 1 endpoint

What it reported

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What moved

1 finding

  • L-ascorbic acid — decreases all-cause mortality

    Evidence strength: limited.Finding
    “Vitamin C use was associated with a significantly lower risk of hospital mortality (PS-matched OR, 0.94; 95% CI 0.90–0.97) (Additional file 2: Table S7).”
    Quoted verbatim from Vitamin C for ≥ 5 days is associated with decreased hospital mortality in sepsis subgroups: a nationwide cohort study..
    Study
    cohort
    Dose
    high-dose intravenous vitamin C, dose not recorded (about 6 g/day assumed from prior Korean studies)
    Population
    Propensity-score-matched adults with sepsis admitted to intensive care in Korea (nationwide claims database); intravenous vitamin C of any duration versus no vitamin C; hospital-period mortality

    Effect 0.94 odds ratio, 95% CI 0.9 to 0.97

    Vitamin C for ≥ 5 days is associated with decreased hospital mortality in sepsis subgroups: a nationwide cohort study.2022PMID:3498359510.1186/s13054-021-03872-3Permalink