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Papers/PMID:34961418

Effects of Berberine on Gut Microbiota in Patients with Mild Metabolic Disorders Induced by Olanzapine.

The American journal of Chinese medicine2021The record

3 findings · 1 compound · 3 endpoints

What it reported

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What moved

3 findings

  • berberine — decreases fasting blood glucose

    Evidence strength: very limited.Findingreplicated ×3
    “FPG, FPI, HOMA-IR, HbA1, TG, BMI, and WC were significantly lower in patients who received berberine compared to placebo after 12 weeks of treatment ([Formula: see text]< 0.05).”
    Quoted verbatim from Effects of Berberine on Gut Microbiota in Patients with Mild Metabolic Disorders Induced by Olanzapine..
    Study
    RCT
    Duration
    3 months
    Population
    patients with schizophrenia, bipolar disorder, or schizoaffective psychosis with olanzapine-induced mild metabolic disorders, continuing olanzapine treatment (background, both arms)

    Effects of Berberine on Gut Microbiota in Patients with Mild Metabolic Disorders Induced by Olanzapine.2021PMID:3496141810.1142/S0192415X21500920Permalink

  • berberine — decreases HOMA-IR

    Evidence strength: very limited.Findingreplicated ×4
    “FPG, FPI, HOMA-IR, HbA1, TG, BMI, and WC were significantly lower in patients who received berberine compared to placebo after 12 weeks of treatment ([Formula: see text]< 0.05).”
    Quoted verbatim from Effects of Berberine on Gut Microbiota in Patients with Mild Metabolic Disorders Induced by Olanzapine..
    Study
    RCT
    Duration
    3 months
    Population
    patients with schizophrenia, bipolar disorder, or schizoaffective psychosis with olanzapine-induced mild metabolic disorders, continuing olanzapine treatment (background, both arms)

    Effects of Berberine on Gut Microbiota in Patients with Mild Metabolic Disorders Induced by Olanzapine.2021PMID:3496141810.1142/S0192415X21500920Permalink

  • berberine — decreases body mass index

    Evidence strength: very limited.Findingreplicated ×3
    “FPG, FPI, HOMA-IR, HbA1, TG, BMI, and WC were significantly lower in patients who received berberine compared to placebo after 12 weeks of treatment ([Formula: see text]< 0.05).”
    Quoted verbatim from Effects of Berberine on Gut Microbiota in Patients with Mild Metabolic Disorders Induced by Olanzapine..
    Study
    RCT
    Duration
    3 months
    Population
    patients with schizophrenia, bipolar disorder, or schizoaffective psychosis with olanzapine-induced mild metabolic disorders, continuing olanzapine treatment (background, both arms)

    Effects of Berberine on Gut Microbiota in Patients with Mild Metabolic Disorders Induced by Olanzapine.2021PMID:3496141810.1142/S0192415X21500920Permalink