Papers/PMID:34732600
N-Acetylcysteine's Renoprotective Effect in Cardiac Surgery: A Systematic Review and Meta-Analysis.
Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia2022The record
1 finding · 1 compound · 1 endpoint · 1 null
What it reported
How to read these marksEvery finding here is a null result.
What did not
1 finding
N-acetyl-L-cysteine — no detected effect on all-cause mortality
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.FindingNull resultreplicated ×1“Meta-analytic estimates for in-hospital mortality showed that there was no statistically significant difference between patients treated with NAC and without, as shown in Supplemental Fig. 6 (OR: 0.85, 95% CI: 0.43–1.68).”
Quoted verbatim from N-Acetylcysteine's Renoprotective Effect in Cardiac Surgery: A Systematic Review and Meta-Analysis.. - Study
- meta-analysis
- Population
- Adults undergoing cardiac surgery, eight randomised trials pooled, NAC versus placebo; in-hospital mortality horizon
Effect 0.85 odds ratio, 95% CI 0.43 to 1.68
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