Papers/PMID:34061894
Comparison of intravenous magnesium sulphate and lidocaine for attenuation of cardiovascular response to laryngoscopy and endotracheal intubation in elective surgical patients at Zewditu Memorial Hospital Addis Ababa, Ethiopia.
PloS one2021The record
1 finding · 1 compound · 1 endpoint
What it reported
How to read these marksWhat moved
1 finding
magnesium(2+) — decreases mean arterial pressure
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.Findingreplicated ×2“Group M compared to group N, mean MAP was significantly lower at immediate, 2nd, 5th and at 7th minutes post-intubation intervals (p<0.001, <0.001, <0.001, = 0.011) respectively.”
Quoted verbatim from Comparison of intravenous magnesium sulphate and lidocaine for attenuation of cardiovascular response to laryngoscopy and endotracheal intubation in elective surgical patients at Zewditu Memorial Hospital Addis Ababa, Ethiopia.. - Study
- cohort
- Dose
- 30 mg/kg magnesium sulphate 50% injected slowly over 5 minutes, 5 minutes before induction
- Population
- Adult ASA I elective surgical patients aged 18-60 induced with thiopental; Group M (magnesium sulphate) versus Group N (thiopental without premedication); post-intubation timepoints from immediate to 7 minutes; observational cohort, anaesthetist's choice of premedication
Comparison of intravenous magnesium sulphate and lidocaine for attenuation of cardiovascular response to laryngoscopy and endotracheal intubation in elective surgical patients at Zewditu Memorial Hospital Addis Ababa, Ethiopia.2021PMID:34061894Permalink