PapersPMID:34058202
The effects of melatonin therapy on the treatment of patients with Non-alcoholic steatohepatitis: A systematic review and Meta-analysis on clinical trial studies.
- 01 · finding
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- 02 · compound
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- 03 · endpoint
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- 04 · null
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melatoninWhat moved
1 findingHow to read these marks →melatonin — decreases alanine aminotransferase
very limitedFinding
“Alanine transaminase levels were significantly lowered with melatonin treatment but not earlier than the 4th week (P = 0.010 and 0.519, respectively).”
Quoted verbatim from The effects of melatonin therapy on the treatment of patients with Non-alcoholic steatohepatitis: A systematic review and Meta-analysis on clinical trial studies. - Study
- meta-analysis
- Population
- NAFLD/NASH patients, pooled across 7 clinical trials of melatonin therapy; reduction significant only from the 4th week of treatment onward, not before