Papers/PMID:34058202
The effects of melatonin therapy on the treatment of patients with Non-alcoholic steatohepatitis: A systematic review and Meta-analysis on clinical trial studies.
European journal of pharmacology2021The record
1 finding drawn from this paper, on 1 compound across 1 endpoint.
What it reported
How to read these marksWhat moved
1 finding
melatonin — decreases alanine aminotransferase
PreliminaryGrade D, Preliminary. Non-human or in vitro only.Finding“Alanine transaminase levels were significantly lowered with melatonin treatment but not earlier than the 4th week (P = 0.010 and 0.519, respectively).”
Quoted verbatim from The effects of melatonin therapy on the treatment of patients with Non-alcoholic steatohepatitis: A systematic review and Meta-analysis on clinical trial studies.. - Study
- meta-analysis
- Population
- NAFLD/NASH patients, pooled across 7 clinical trials of melatonin therapy; reduction significant only from the 4th week of treatment onward, not before