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Papers/PMID:34040600

Immunomodulatory and Mechanistic Considerations of Hibiscus sabdariffa (HS) in Dysfunctional Immune Responses: A Systematic Review.

Frontiers in immunology2021The record

1 finding · 1 compound · 1 endpoint · 1 null

What it reported

How to read these marks

Every finding here is a null result.

What did not

1 finding

  • Hibiscus sabdariffa — no detected effect on C-reactive protein concentration

    Evidence strength: moderate.FindingNull resultreplicated ×1
    “The levels of CRP (: n=4; pooled SMD: 0.05; 95% CI: -0.26, 0.36; P = 0.75), IL-10 (: n=4; pooled SMD:-0.38; 95% CI: -1.67, 0.91; P = 0.56), and iNOS (: n=2; pooled SMD:-0.69; 95% CI: -1.60, 0.23 P = 0.14) were not significantly affected by HS treatment.”
    Quoted verbatim from Immunomodulatory and Mechanistic Considerations of Hibiscus sabdariffa (HS) in Dysfunctional Immune Responses: A Systematic Review..
    Study
    meta-analysis
    Population
    Four included studies of Hibiscus sabdariffa calyx extract against untreated control groups; the review's Table 2 lists the CRP studies as healthy humans, humans with metabolic syndrome and men at low cardiovascular risk

    Effect 0.05 standardised mean difference, 95% CI -0.26 to 0.36

    Immunomodulatory and Mechanistic Considerations of Hibiscus sabdariffa (HS) in Dysfunctional Immune Responses: A Systematic Review.2021PMID:3404060010.3389/fimmu.2021.550670Permalink