Papers/PMID:33957167
Neurocognitive effects of melatonin treatment in healthy adults and individuals with Alzheimer's disease and insomnia: A systematic review and meta-analysis of randomized controlled trials.
Neuroscience and biobehavioral reviews2021The record
1 finding drawn from this paper, on 1 compound across 1 endpoint.
What it reported
How to read these marksWhat moved
1 finding
melatonin — increases Mini-Mental State Examination total score
PreliminaryGrade D, Preliminary. Non-human or in vitro only.Finding“AD patients receiving >12 weeks of melatonin treatment improved mini-mental state examination (MMSE) score [MD: 1.82 (1.01; 2.63) p < 0.0001].”
Quoted verbatim from Neurocognitive effects of melatonin treatment in healthy adults and individuals with Alzheimer's disease and insomnia: A systematic review and meta-analysis of randomized controlled trials.. - Study
- meta-analysis
- Population
- Alzheimer's disease patients receiving more than 12 weeks of melatonin treatment (meta-analysis of RCTs)
Effect 1.82 mean difference, 95% CI 1.01 to 2.63