Papers/PMID:33806529
Melatonin Supplementation for Six Weeks Had No Effect on Arterial Stiffness and Mitochondrial DNA in Women Aged 55 Years and Older with Insomnia: A Double-Blind Randomized Controlled Study.
International journal of environmental research and public health2021The record
1 finding · 1 compound · 1 endpoint · 1 null
What it reported
How to read these marksEvery finding here is a null result.
What did not
1 finding
melatonin — no detected effect on HOMA-IR
Evidence strength: moderate.FindingNull resultreplicated ×1“There were no intergroup differences in CAVI, mtDNA, HOMA-IR, or SBP from the baseline to week six between the placebo and melatonin groups.”
Quoted verbatim from Melatonin Supplementation for Six Weeks Had No Effect on Arterial Stiffness and Mitochondrial DNA in Women Aged 55 Years and Older with Insomnia: A Double-Blind Randomized Controlled Study.. - Study
- RCT
- Duration
- 6 weeks
- Dose
- 2 mg prolonged-release melatonin (Circadin 2 mg PR) once a day, two hours before sleep, for six weeks
- Population
- Women aged 55 years and older with insomnia (PSQI of 5 or more), untreated; change from baseline to week six
Melatonin Supplementation for Six Weeks Had No Effect on Arterial Stiffness and Mitochondrial DNA in Women Aged 55 Years and Older with Insomnia: A Double-Blind Randomized Controlled Study.2021PMID:3380652910.3390/ijerph18052561Permalink