Papers/PMID:33745609
The effects of magnesium supplementation on serum level of brain derived neurotrophic factor (BDNF) and depression status in patients with depression.
Clinical nutrition ESPEN2021The record
1 finding · 1 compound · 1 endpoint · 1 null
What it reported
How to read these marksEvery finding here is a null result.
What did not
1 finding
magnesium(2+) — no detected effect on brain-derived neurotrophic factor (BDNF) concentration
Evidence strength: very limited.FindingNull result“At the end of intervention, supplementation with magnesium oxide had a significant effect on Beck's test (P = 0.01) and serum magnesium (P = 0.001), but had no significant effect on BDNF levels (P = 0.507) between the two groups.”
Quoted verbatim from The effects of magnesium supplementation on serum level of brain derived neurotrophic factor (BDNF) and depression status in patients with depression.. - Study
- RCT
- Duration
- 8 weeks
- Dose
- 500 mg magnesium oxide daily for 8 weeks
- Population
- Depressed patients, double-blind randomised trial, magnesium oxide versus placebo
The effects of magnesium supplementation on serum level of brain derived neurotrophic factor (BDNF) and depression status in patients with depression.2021PMID:3374560910.1016/j.clnesp.2020.12.022Permalink