Papers/PMID:33650299
Effect of selenium on thyroid autoimmunity and regulatory T cells in patients with Hashimoto's thyroiditis: A prospective randomized-controlled trial.
Clinical and translational science2021The record
1 finding · 1 compound · 1 endpoint
What it reported
How to read these marksWhat moved
1 finding
selenium atom — decreases serum thyroid peroxidase antibody (TPOAb) titre
Evidence strength: moderate.Findingreplicated ×1“In the Se‐treated group, TPOAb levels were significantly lower than that in study entry after 3 and 6 months, and the reductions were statistically different compared with the control group at 6 months (ΔTPOAb [IU/ml] = −28.4 [−103.9, 0] vs. 0 [−18.1, 20.5], p = 0.001).”
Quoted verbatim from Effect of selenium on thyroid autoimmunity and regulatory T cells in patients with Hashimoto's thyroiditis: A prospective randomized-controlled trial.. - Study
- RCT
- Dose
- 200 μg/day selenious yeast tablet for at least 6 months
- Population
- Patients with Hashimoto's thyroiditis, 43 randomised to selenious yeast tablet and 47 to no treatment, open-label, change from baseline at 6 months
Effect of selenium on thyroid autoimmunity and regulatory T cells in patients with Hashimoto's thyroiditis: A prospective randomized-controlled trial.2021PMID:3365029910.1111/cts.12993Permalink