Papers/PMID:33596883
The effect of L-Carnitine supplementation on clinical symptoms, C-reactive protein and malondialdehyde in obese women with knee osteoarthritis: a double blind randomized controlled trial.
BMC musculoskeletal disorders2021The record
2 findings · 1 compound · 2 endpoints · 2 null
What it reported
How to read these marksEvery finding here is a null result.
What did not
2 findings
(R)-carnitine — no detected effect on fat mass
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.FindingNull result“There was no significant difference between LCG and PLG, in the mean changes of hip circumference, visceral fat, free fat mass, fat mass, lipid profiles, CRP, MDA as well as stiffness, physical function, decrease of pain and total scores (P > 0.05).”
Quoted verbatim from The effect of L-Carnitine supplementation on clinical symptoms, C-reactive protein and malondialdehyde in obese women with knee osteoarthritis: a double blind randomized controlled trial.. - Study
- RCT
- Duration
- 3 months
- Dose
- 1000 mg L-carnitine for 12 weeks, both arms on a low-calorie diet
- Population
- Obese women with knee osteoarthritis, all on a low-calorie diet
The effect of L-Carnitine supplementation on clinical symptoms, C-reactive protein and malondialdehyde in obese women with knee osteoarthritis: a double blind randomized controlled trial.2021PMID:33596883Permalink
(R)-carnitine — no detected effect on C-reactive protein concentration
LimitedEvidence strength: limited. Human evidence with several recorded weaknesses, or a design that tops out at limited.FindingNull result“There was no significant difference between LCG and PLG, in the mean changes of hip circumference, visceral fat, free fat mass, fat mass, lipid profiles, CRP, MDA as well as stiffness, physical function, decrease of pain and total scores (P > 0.05).”
Quoted verbatim from The effect of L-Carnitine supplementation on clinical symptoms, C-reactive protein and malondialdehyde in obese women with knee osteoarthritis: a double blind randomized controlled trial.. - Study
- RCT
- Duration
- 3 months
- Dose
- 1000 mg L-carnitine for 12 weeks, both arms on a low-calorie diet
- Population
- Obese women with knee osteoarthritis, all on a low-calorie diet
The effect of L-Carnitine supplementation on clinical symptoms, C-reactive protein and malondialdehyde in obese women with knee osteoarthritis: a double blind randomized controlled trial.2021PMID:33596883Permalink