Papers/PMID:32454800
Effect of Nigella sativa Supplementation on Oxidative Stress and Antioxidant Parameters: A Meta-Analysis of Randomized Controlled Trials.
TheScientificWorldJournal2020The record
2 findings · 1 compound · 2 endpoints · 2 null
What it reported
How to read these marksEvery finding here is a null result.
What did not
2 findings
Nigella sativa — no detected effect on malondialdehyde (circulating)
Evidence strength: moderate.FindingNull result“Analysis from four studies showed that NS supplementation did not significantly reduce MDA (Weighted Mean Differences (WMD): −0.532, 95% CI: −1.192 to 0.128, p=0.114)) compared to controls.”
Quoted verbatim from Effect of Nigella sativa Supplementation on Oxidative Stress and Antioxidant Parameters: A Meta-Analysis of Randomized Controlled Trials.. - Study
- meta-analysis
- Dose
- 500 mg/day, 2 g/day or 3 g/day across pooled trials
- Population
- Adults aged 18 to 60 with type 2 diabetes, rheumatoid arthritis, obesity or ulcerative colitis, pooled from four placebo-controlled randomised trials
Effect -0.532 mean difference, 95% CI -1.192 to 0.128
Effect of Nigella sativa Supplementation on Oxidative Stress and Antioxidant Parameters: A Meta-Analysis of Randomized Controlled Trials.2020PMID:3245480010.1155/2020/2390706Permalink
Nigella sativa — no detected effect on total antioxidant capacity
Evidence strength: moderate.FindingNull result“Analysis from four studies showed that NS supplementation did not significantly increase TAC (Weighted Mean Differences (WMD): 0.219, 95% CI: −0.136 to 0.573, p=0.227)) as compared to controls.”
Quoted verbatim from Effect of Nigella sativa Supplementation on Oxidative Stress and Antioxidant Parameters: A Meta-Analysis of Randomized Controlled Trials.. - Study
- meta-analysis
- Dose
- 500 mg/day, 2 g/day or 3 g/day across pooled trials
- Population
- Adults aged 18 to 60 with type 2 diabetes, rheumatoid arthritis, obesity or ulcerative colitis, pooled from four placebo-controlled randomised trials
Effect 0.219 mean difference, 95% CI -0.136 to 0.573
Effect of Nigella sativa Supplementation on Oxidative Stress and Antioxidant Parameters: A Meta-Analysis of Randomized Controlled Trials.2020PMID:3245480010.1155/2020/2390706Permalink