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Papers/PMID:32374278

Efficacy of weekly administration of cholecalciferol on parathyroid hormone in stable kidney-transplanted patients with CKD stage 1-3.

Clinical chemistry and laboratory medicine2020The record

1 finding · 1 compound · 1 endpoint

What it reported

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What moved

1 finding

  • calciol — increases serum 25-hydroxyvitamin D concentration

    Evidence strength: very limited.Findingreplicated ×33
    “However, 25(OH)D levels were significantly higher at both 6 (63.5 vs. 30.3 nmol/L, p < 0.001) and 12 months (69.4 vs. 30 nmol/L, p < 0.001) in treated vs. untreated patients, corresponding with a significant reduction in PTH at both 6 (112 vs. 161 pg/mL) and 12 months (109 vs. 154 pg/mL) in treated vs. untreated patients, respectively (p < 0.001 for both).”
    Quoted verbatim from Efficacy of weekly administration of cholecalciferol on parathyroid hormone in stable kidney-transplanted patients with CKD stage 1-3..
    Study
    cohort
    Dose
    oral cholecalciferol 7500-8750 IU weekly for 12 months
    Population
    Stable kidney-transplant recipients with chronic kidney disease stage 1-3, retrospective cohort; treated recipients compared with untreated age- and gender-matched recipients; values at 6 and 12 months

    Efficacy of weekly administration of cholecalciferol on parathyroid hormone in stable kidney-transplanted patients with CKD stage 1-3.2020PMID:3237427810.1515/cclm-2020-0282Permalink