Papers/PMID:32147078
The effect of vitamin E supplementation on biomarkers of endothelial function and inflammation among hemodialysis patients: A double-blinded randomized clinical trial.
Complementary therapies in medicine2020The record
2 findings · 1 compound · 2 endpoints · 2 null
What it reported
How to read these marksEvery finding here is a null result.
What did not
2 findings
α-tocopherol — no detected effect on C-reactive protein concentration
Evidence strength: very limited.FindingNull result“Our results showed that 10 weeks of supplementation with 600 IU alpha-tocopherol improved ICAM-1 and VCAM-1 levels, but did not have any effect on the serum concentration of IL-6 and hs-CRP in hemodialysis patients.”
Quoted verbatim from The effect of vitamin E supplementation on biomarkers of endothelial function and inflammation among hemodialysis patients: A double-blinded randomized clinical trial.. - Study
- RCT
- Duration
- 2 months
- Dose
- 600 IU alpha-tocopherol soft gels (200 IU three times daily)
- Population
- Hemodialysis patients aged 20-60 years; pre-dialysis serum; placebo soft gel controls
The effect of vitamin E supplementation on biomarkers of endothelial function and inflammation among hemodialysis patients: A double-blinded randomized clinical trial.2020PMID:3214707810.1016/j.ctim.2020.102357Permalink
α-tocopherol — no detected effect on interleukin-6 concentration
Evidence strength: very limited.FindingNull resultreplicated ×1“Our results showed that 10 weeks of supplementation with 600 IU alpha-tocopherol improved ICAM-1 and VCAM-1 levels, but did not have any effect on the serum concentration of IL-6 and hs-CRP in hemodialysis patients.”
Quoted verbatim from The effect of vitamin E supplementation on biomarkers of endothelial function and inflammation among hemodialysis patients: A double-blinded randomized clinical trial.. - Study
- RCT
- Duration
- 2 months
- Dose
- 600 IU alpha-tocopherol soft gels (200 IU three times daily)
- Population
- Hemodialysis patients aged 20-60 years; pre-dialysis serum; placebo soft gel controls
The effect of vitamin E supplementation on biomarkers of endothelial function and inflammation among hemodialysis patients: A double-blinded randomized clinical trial.2020PMID:3214707810.1016/j.ctim.2020.102357Permalink