PapersPMID:32063564
L-Carnosine combination therapy for major depressive disorder: A randomized, double-blind, placebo-controlled trial.
What moved
1 findingHow to read these marks →- Increases depression remission rate
very limited
“Patients in the L-Carnosine group experienced significantly greater response and remission rate than the placebo group [Ps = 0.023 and 0.012; respectively].”
- Study
- RCT
- Duration
- 6 weeks
- Dose studied
- 400 mg L-Carnosine twice daily plus citalopram versus placebo plus citalopram, 6 weeks
- Population
- Adults with major depressive disorder (DSM-V, HAM-D 19 or higher), all taking citalopram up to 40 mg/day in both arms
Study record
- Design
- randomised controlled trial
- Species
- human
- Population
- patients with major depressive disorder (DSM-V), HAM-D score of 19 or more, all taking citalopram
- Participants
- 58
- Comparator
- placebo
- Duration
- 42 days
- Endpoints measured
- 6