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Papers/PMID:31077299

A Prospective Study of Serum Vitamin E and 28-Year Risk of Lung Cancer.

Journal of the National Cancer Institute2020The record

1 finding · 1 compound · 1 endpoint

What it reported

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1 finding

  • α-tocopherol — decreases lung cancer incidence

    Evidence strength: very limited.Findingreplicated ×1
    “After adjustment for age, body mass index, smoking intensity and duration, serum total cholesterol, and trial intervention group, we found lower lung cancer risk in men with high baseline alpha-tocopherol (fifth quintile [Q5] vs Q1, hazard ratio [HR] = 0.76, 95% confidence interval [CI] = 0.66 to 0.87, Ptrend < .001).”
    Quoted verbatim from A Prospective Study of Serum Vitamin E and 28-Year Risk of Lung Cancer..
    Study
    cohort
    Population
    22,781 male smokers in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study; highest vs lowest quintile of baseline serum alpha-tocopherol, up to 28 years of follow-up

    Effect 0.76 hazard ratio, 95% CI 0.66 to 0.87

    A Prospective Study of Serum Vitamin E and 28-Year Risk of Lung Cancer.2020PMID:3107729910.1093/jnci/djz077Permalink