Endpoint
Lung cancer incidence
Tumors or cancer of the lung.
CAT:outcome/lung-cancer-incidencereported in risk ratio1 finding from 1 compound
What moved it
How to read these marks1 finding · 1 compound · by evidence strength
| Compound | Direction | Findings | Strongest evidence |
|---|---|---|---|
| glucosamine | down | 1 | Evidence strength: limited. Human evidence with several recorded weaknesses, or a design that tops out at limited. |
Reported to move it
1 finding
glucosamine — decreases
LimitedEvidence strength: limited. Human evidence with several recorded weaknesses, or a design that tops out at limited.Finding“During a median of 12.5 years follow-up, glucosamine use was significantly associated with an increased risk of overall cancer [HR, 1.04; 95% confidence interval (CI), 1.01-1.06], skin cancer (HR, 1.11; 95% CI, 1.07-1.15), and prostate cancer (HR, 1.07; 95% CI, 1.01-1.13), and with a reduced risk of lung cancer (HR, 0.88; 95% CI, 0.79-0.97) after adjusting for potential confounders.”
Quoted verbatim from Regular Glucosamine Use May Have Different Roles in the Risk of Site-Specific Cancers: Findings from a Large Prospective Cohort.. - Study
- cohort
- Population
- UK Biobank adults free of cancer at baseline, regular glucosamine users versus non-users
Effect 0.88 hazard ratio, 95% CI 0.79 to 0.97
Regular Glucosamine Use May Have Different Roles in the Risk of Site-Specific Cancers: Findings from a Large Prospective Cohort.2023PMID:36716122Permalink
How it is measured
Incident lung cancer diagnoses over the follow-up the source states.
Measured, not recorded
- Subject
- lung cancer incidence
- Measurements
- 4 measurements
- Recorded as a finding
- No
Show what was measured
lung cancer incidence
decreases, p = 0.018
The pooled relative risk (RR) indicated a significant association between lung cancer incidence and magnesium intake (RR = 0.88, 95% CI = 0.79 to 0.98; p = 0.018)
PMID:31303138 · one of two readings recorded this
lung cancer incidence
decreases, p = 0.034
where doses of magnesium intake lower than 300 mg/d significantly decreased lung cancer risk (RR = 0.83, 95% CI = 0.70 to 0.99; p = 0.034)
PMID:31303138 · one of two readings recorded this
lung cancer incidence
no effect, p = 0.076
Increasing magnesium intake doses to over 300 mg/d did not reduce the incidence of lung cancer (RR = 0.89, 95% CI = 0.78 to 1.01; p = 0.076)
PMID:31303138 · one of two readings recorded this
lung cancer incidence
decreases, n = 450207
glucosamine use was significantly associated with an increased risk of overall cancer [HR, 1.04; 95% confidence interval (CI), 1.01-1.06], skin cancer (HR, 1.11; 95% CI, 1.07-1.15), and prostate cancer (HR, 1.07; 95% CI, 1.01-1.13), and with a reduced risk of lung cancer (HR, 0.88; 95% CI, 0.79-0.97)
PMID:36716122 · one of two readings recorded this
Sources cited
1 paper
- Subject
- lung cancer incidence
- Findings
- 1
- Papers
- 1