Papers/PMID:30802939
Iodine supplementation for the prevention of mortality and adverse neurodevelopmental outcomes in preterm infants.
The Cochrane database of systematic reviews2019The record
1 finding · 1 compound · 1 endpoint · 1 null
What it reported
How to read these marksEvery finding here is a null result.
What did not
1 finding
iodide — no detected effect on death before hospital discharge (preterm infants)
Evidence strength: very limited.FindingNull result“Analyses found no effect of iodine supplementation on mortality before hospital discharge (typical RR 1.01, 95% CI 0.72 to 1.42; 2 studies, 1380 infants) or on neurodevelopmental assessments at two years post-term (Bayley Scales of Infant and Toddler Development, Third Edition main domain composite scores: cognitive: MD -0.30, 95% CI -2.44 to 1.84; motor: MD 0.20, 95% CI -2.15 to 2.55; language: MD -0.10, 95% CI -2.50 to 2.30; 1 study, 1259 infants).”
Quoted verbatim from Iodine supplementation for the prevention of mortality and adverse neurodevelopmental outcomes in preterm infants.. - Study
- meta-analysis
- Participants
- 1,380
- Population
- Preterm infants, mostly born before 32 weeks' gestation, in two randomised trials supplementing enteral or parenteral feeds with iodine (as iodide salt) versus placebo or no supplementation; abstract-only reading
Effect 1.01 risk ratio, 95% CI 0.72 to 1.42
Iodine supplementation for the prevention of mortality and adverse neurodevelopmental outcomes in preterm infants.2019PMID:3080293910.1002/14651858.CD005253.pub3Permalink