Papers/PMID:30795785
The effects of crocin on psychological parameters in patients under methadone maintenance treatment: a randomized clinical trial.
Substance abuse treatment, prevention, and policy2019The record
2 findings · 1 compound · 2 endpoints
What it reported
How to read these marksWhat moved
2 findings
crocin-1 — decreases beck Depression Inventory (BDI) total score
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.Finding“After 8-week intervention, crocin significantly decreased Beck Depression Inventory (b - 6.66; 95% CI, - 9.88, - 3.45; P < 0.0001), Beck Anxiety Inventory (b - 4.35; 95% CI, - 5.94, - 2.75; P < 0.0001), general health questionnaire (b - 4.45; 95% CI, - 7.68, - 1.22; P = 0.008) and Pittsburgh Sleep Quality Index (b - 2.73; 95% CI, - 3.74, - 1.73; P < 0.0001) in patients under MMT, compared with the placebo.”
Quoted verbatim from The effects of crocin on psychological parameters in patients under methadone maintenance treatment: a randomized clinical trial.. - Study
- RCT
- Duration
- 8 weeks
- Dose
- 30 mg/day crocin (15 mg twice daily)
- Population
- Patients under methadone maintenance treatment (methadone in both arms); crocin 30 mg/day versus placebo
The effects of crocin on psychological parameters in patients under methadone maintenance treatment: a randomized clinical trial.2019PMID:30795785Permalink
crocin-1 — decreases pittsburgh Sleep Quality Index global score
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.Finding“After 8-week intervention, crocin significantly decreased Beck Depression Inventory (b - 6.66; 95% CI, - 9.88, - 3.45; P < 0.0001), Beck Anxiety Inventory (b - 4.35; 95% CI, - 5.94, - 2.75; P < 0.0001), general health questionnaire (b - 4.45; 95% CI, - 7.68, - 1.22; P = 0.008) and Pittsburgh Sleep Quality Index (b - 2.73; 95% CI, - 3.74, - 1.73; P < 0.0001) in patients under MMT, compared with the placebo.”
Quoted verbatim from The effects of crocin on psychological parameters in patients under methadone maintenance treatment: a randomized clinical trial.. - Study
- RCT
- Duration
- 8 weeks
- Dose
- 30 mg/day crocin (15 mg twice daily)
- Population
- Patients under methadone maintenance treatment (methadone in both arms); crocin 30 mg/day versus placebo
The effects of crocin on psychological parameters in patients under methadone maintenance treatment: a randomized clinical trial.2019PMID:30795785Permalink