Papers/PMID:29750366
Feasibility and Acceptability of Maternal Choline Supplementation in Heavy Drinking Pregnant Women: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial.
Alcoholism, clinical and experimental research2018The record
1 finding · 1 compound · 1 endpoint
What it reported
How to read these marksWhat moved
1 finding
choline — increases plasma choline concentration
Evidence strength: moderate.Findingreplicated ×2“By 4 weeks, plasma choline concentrations were already significantly higher in the choline supplementation than the placebo group, and this group difference continued to be evident at 12 weeks.”
Quoted verbatim from Feasibility and Acceptability of Maternal Choline Supplementation in Heavy Drinking Pregnant Women: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial.. - Study
- RCT
- Dose
- 2 g choline per day as two doses of 1.25 g choline bitartrate (1 g choline cation each), from enrollment until delivery
- Population
- Heavy-drinking pregnant women recruited in mid-pregnancy in Cape Town, South Africa; plasma sampled at 4 and 12 weeks after randomization
Feasibility and Acceptability of Maternal Choline Supplementation in Heavy Drinking Pregnant Women: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial.2018PMID:2975036610.1111/acer.13768Industry fundedPermalink