Papers/PMID:29706321
Resveratrol improves ex vivo mitochondrial function but does not affect insulin sensitivity or brown adipose tissue in first degree relatives of patients with type 2 diabetes.
Molecular metabolism2018The record
1 finding · 1 compound · 1 endpoint · 1 null
What it reported
How to read these marksEvery finding here is a null result.
What did not
1 finding
resveratrol — no detected effect on glycated haemoglobin (HbA1c)
Evidence strength: very limited.FindingNull result“Furthermore, fasting plasma FFA levels were comparable between treatments and were similarly suppressed by insulin (Table 1), and no changes in fasting insulin, glucose, HbA1c levels, or other plasma markers related to metabolic health were found upon resveratrol supplementation (Table S2).”
Quoted verbatim from Resveratrol improves ex vivo mitochondrial function but does not affect insulin sensitivity or brown adipose tissue in first degree relatives of patients with type 2 diabetes.. - Study
- crossover
- Duration
- 4 weeks
- Dose
- 150 mg/day trans-resveratrol vs placebo
- Population
- Thirteen overweight male first-degree relatives of patients with type 2 diabetes at increased risk of developing T2D, double-blind crossover
Resveratrol improves ex vivo mitochondrial function but does not affect insulin sensitivity or brown adipose tissue in first degree relatives of patients with type 2 diabetes.2018PMID:2970632110.1016/j.molmet.2018.04.004Industry fundedPermalink