Papers/PMID:29457023
Effect of Zinc Supplementation on Maintenance Hemodialysis Patients: A Systematic Review and Meta-Analysis of 15 Randomized Controlled Trials.
BioMed research international2017The record
2 findings · 1 compound · 2 endpoints
What it reported
How to read these marksWhat moved
2 findings
Zn(2+) — increases superoxide dismutase activity
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.Finding“In the crude analysis, we found that levels of serum zinc, dietary protein intake, and SOD in the zinc supplementation group were higher than levels in control group after treatment.”
Quoted verbatim from Effect of Zinc Supplementation on Maintenance Hemodialysis Patients: A Systematic Review and Meta-Analysis of 15 Randomized Controlled Trials.. - Study
- meta-analysis
- Dose
- elemental zinc 11 to 100 mg across trials
- Population
- Maintenance hemodialysis patients in 15 pooled randomised trials of oral zinc supplementation against placebo or blank control
Effect of Zinc Supplementation on Maintenance Hemodialysis Patients: A Systematic Review and Meta-Analysis of 15 Randomized Controlled Trials.2017PMID:29457023Permalink
Zn(2+) — decreases C-reactive protein concentration
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.Findingreplicated ×3“CRP and MDA levels were lower after zinc supplementation (CRP: WMD = −8.618, 95% CI = −15.579 to −1.656, P = 0.015; MDA: WMD = −1.275, 95% CI = −1.945 to −0.605, P < 0.001).”
Quoted verbatim from Effect of Zinc Supplementation on Maintenance Hemodialysis Patients: A Systematic Review and Meta-Analysis of 15 Randomized Controlled Trials.. - Study
- meta-analysis
- Dose
- elemental zinc 11 to 100 mg across trials
- Population
- Maintenance hemodialysis patients in 15 pooled randomised trials of oral zinc supplementation against placebo or blank control
Effect -8.618 mean difference, 95% CI -15.579 to -1.656
Effect of Zinc Supplementation on Maintenance Hemodialysis Patients: A Systematic Review and Meta-Analysis of 15 Randomized Controlled Trials.2017PMID:29457023Permalink