Papers/PMID:29191850
Long-Term Effect of Pravastatin on Carotid Intima-Media Complex Thickness: The J-STARS Echo Study (Japan Statin Treatment Against Recurrent Stroke).
Stroke2018The record
2 findings · 1 compound · 2 endpoints
What it reported
How to read these marksWhat moved
2 findings
pravastatin — decreases triglycerides
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.Findingreplicated ×1“The average of differences for triglycerides until 5 years was significantly reduced with 10 mg daily of pravastatin(P=0.023).”
Quoted verbatim from Long-Term Effect of Pravastatin on Carotid Intima-Media Complex Thickness: The J-STARS Echo Study (Japan Statin Treatment Against Recurrent Stroke).. - Study
- RCT
- Dose
- 10 mg daily
- Population
- Japanese patients aged 45-80 with noncardioembolic ischemic stroke and serum total cholesterol 180-240 mg/dL without statins, pravastatin 10 mg daily versus no statin (open-label); J-STARS Echo substudy
Long-Term Effect of Pravastatin on Carotid Intima-Media Complex Thickness: The J-STARS Echo Study (Japan Statin Treatment Against Recurrent Stroke).2018PMID:29191850Permalink
pravastatin — decreases total cholesterol (TC)
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.Findingreplicated ×1“Total cholesterol and LDLC were significantly reduced with 10 mg daily of pravastatin by 12% and 19%, respectively, at the 1-year follow-up and continuously thereafter.”
Quoted verbatim from Long-Term Effect of Pravastatin on Carotid Intima-Media Complex Thickness: The J-STARS Echo Study (Japan Statin Treatment Against Recurrent Stroke).. - Study
- RCT
- Dose
- 10 mg daily
- Population
- Japanese patients aged 45-80 with noncardioembolic ischemic stroke and serum total cholesterol 180-240 mg/dL without statins, pravastatin 10 mg daily versus no statin (open-label); J-STARS Echo substudy
Long-Term Effect of Pravastatin on Carotid Intima-Media Complex Thickness: The J-STARS Echo Study (Japan Statin Treatment Against Recurrent Stroke).2018PMID:29191850Permalink