Papers/PMID:29127425
The effects of vitamin E or lipoic acid supplementation on oxyphytosterols in subjects with elevated oxidative stress: a randomized trial.
Scientific reports2017The record
1 finding · 1 compound · 1 endpoint · 1 null
What it reported
How to read these marksEvery finding here is a null result.
What did not
1 finding
lipoic acid — no detected effect on glycated haemoglobin (HbA1c)
Evidence strength: moderate.FindingNull resultreplicated ×1“Plasma glucose, HbA1c, FGF-19, FGF-21, serum plant sterols and lathosterol and cholestanol concentrations were comparable between the vitamin E, lipoic acid and control periods (Table 3).”
Quoted verbatim from The effects of vitamin E or lipoic acid supplementation on oxyphytosterols in subjects with elevated oxidative stress: a randomized trial.. - Study
- crossover
- Duration
- 4 weeks
- Dose
- 600 mg/day R-lipoic acid (200 mg three times daily) with meals
- Population
- Adults with impaired glucose tolerance or type 2 diabetes, randomized placebo-controlled three-period crossover (4-week periods, 4-week washouts); the other arm was vitamin E
The effects of vitamin E or lipoic acid supplementation on oxyphytosterols in subjects with elevated oxidative stress: a randomized trial.2017PMID:2912742510.1038/s41598-017-15615-yPermalink