Papers/PMID:29080862
Plasma Metabolites From Choline Pathway and Risk of Cardiovascular Disease in the PREDIMED (Prevention With Mediterranean Diet) Study.
Journal of the American Heart Association2017The record
1 finding · 1 compound · 1 endpoint
What it reported
How to read these marksWhat moved
1 finding
choline — increases incidence of cardiovascular disease (composite)
Evidence strength: very limited.Finding“Compared with participants in the lowest quartile of choline, those in the highest quartile had a significantly higher risk of CVD after adjusting for cardiovascular risk factors (HR [95% CI], 1.72 [1.05–2.81]; P=0.01 for trend).”
Quoted verbatim from Plasma Metabolites From Choline Pathway and Risk of Cardiovascular Disease in the PREDIMED (Prevention With Mediterranean Diet) Study.. - Study
- cohort
- Population
- Adults aged 55 to 80 years at high cardiovascular risk, free of CVD at baseline, in a case-cohort study nested in the PREDIMED trial; exposure is baseline plasma choline, highest versus lowest quartile
Effect 1.72 hazard ratio, 95% CI 1.05 to 2.81
Plasma Metabolites From Choline Pathway and Risk of Cardiovascular Disease in the PREDIMED (Prevention With Mediterranean Diet) Study.2017PMID:2908086210.1161/JAHA.117.006524Permalink