Papers/PMID:28662656
Effect of vitamin E on oxidative stress level in blood, synovial fluid, and synovial tissue in severe knee osteoarthritis: a randomized controlled study.
BMC musculoskeletal disorders2017The record
1 finding · 1 compound · 1 endpoint
What it reported
How to read these marksWhat moved
1 finding
α-tocopherol — decreases malondialdehyde (circulating)
Evidence strength: moderate.Finding“The post-intervention nitrite concentration in Group B was lower than that in Group A, but the difference was not significant (p = 0.19); however, the post-intervention MDA level in Group B was significantly lower than that in Group A (p = 0.02).”
Quoted verbatim from Effect of vitamin E on oxidative stress level in blood, synovial fluid, and synovial tissue in severe knee osteoarthritis: a randomized controlled study.. - Study
- RCT
- Duration
- 2 months
- Dose
- 400 IU vitamin E orally once daily for 2 months
- Population
- Patients with late-stage knee osteoarthritis (Kellgren-Lawrence grade 3-4) scheduled for total knee arthroplasty, plasma sample after 2 months; placebo in the comparator arm; acetaminophen allowed as needed in both arms
Effect of vitamin E on oxidative stress level in blood, synovial fluid, and synovial tissue in severe knee osteoarthritis: a randomized controlled study.2017PMID:2866265610.1186/s12891-017-1637-7Permalink