Papers/PMID:28592515
Intragastric Lysine Lowers the Circulating Glucose and Insulin Responses to a Mixed-Nutrient Drink without Slowing Gastric Emptying in Healthy Adults.
The Journal of nutrition2017The record
2 findings · 1 compound · 2 endpoints · 1 null
What it reported
How to read these marksWhat moved
1 finding
L-lysine — increases plasma glucagon
Evidence strength: very limited.Finding“Plasma glucagon at both 15 min (20.7% ± 4.7%, P < 0.001) and 60 min (14.1% ± 5.4%, P < 0.05) and the glucagon AUC0-60min (P < 0.01) were greater after lysine than after the control.”
Quoted verbatim from Intragastric Lysine Lowers the Circulating Glucose and Insulin Responses to a Mixed-Nutrient Drink without Slowing Gastric Emptying in Healthy Adults.. - Study
- crossover
- Dose
- 5 or 10 g l-lysine in 200 mL intragastric infusion, single dose, pooled
- Population
- 12 healthy adults, randomised crossover; intragastric lysine 5 or 10 g pooled, then mixed-nutrient drink; compared with control solution
Intragastric Lysine Lowers the Circulating Glucose and Insulin Responses to a Mixed-Nutrient Drink without Slowing Gastric Emptying in Healthy Adults.2017PMID:2859251510.3945/jn.117.252213Permalink
What did not
1 finding
L-lysine — no detected effect on ad libitum test-meal energy intake
Evidence strength: very limited.FindingNull result“Lysine did not slow gastric emptying, and there was no effect on energy intake.”
Quoted verbatim from Intragastric Lysine Lowers the Circulating Glucose and Insulin Responses to a Mixed-Nutrient Drink without Slowing Gastric Emptying in Healthy Adults.. - Study
- crossover
- Dose
- 5 or 10 g l-lysine in 200 mL intragastric infusion, single dose, pooled
- Population
- 12 healthy adults, randomised crossover; buffet-style meal 60-90 min after intragastric lysine pooled 5 and 10 g versus control solution
Intragastric Lysine Lowers the Circulating Glucose and Insulin Responses to a Mixed-Nutrient Drink without Slowing Gastric Emptying in Healthy Adults.2017PMID:2859251510.3945/jn.117.252213Permalink