Endpoint
Plasma glucagon
A 29-amino acid pancreatic peptide derived from proglucagon which is also the precursor of intestinal glucagon-like peptides. Glucagon is secreted by pancreatic alpha cells and plays an important role in regulation of blood glucose concentration, ketone metabolism, and several other biochemical and physiological processes. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p1511)
CAT:outcome/plasma-glucagonreported in pg/mL
How it is measured
Plasma glucagon concentration by immunoassay, sampled before and serially after an intragastric amino-acid preload and a fixed mixed-nutrient drink.