Papers/PMID:28575224
Response to Antenatal Cholecalciferol Supplementation Is Associated With Common Vitamin D-Related Genetic Variants.
The Journal of clinical endocrinology and metabolism2017The record
1 finding · 1 compound · 1 endpoint
What it reported
How to read these marksWhat moved
1 finding
calciol — increases serum 25-hydroxyvitamin D concentration
Evidence strength: moderate.Findingreplicated ×33“25(OH)D was similar at baseline between the two groups but significantly higher in the women randomized to cholecalciferol at 34 weeks of gestation [mean (standard deviation), 67.3 (20.8) nmol/L] compared with placebo [mean (standard deviation), 43.0 (22.2) nmol/L, P < 0.001].”
Quoted verbatim from Response to Antenatal Cholecalciferol Supplementation Is Associated With Common Vitamin D-Related Genetic Variants.. - Study
- RCT
- Dose
- cholecalciferol 1000 IU/d from before 17 weeks of gestation until delivery; assessed at 34 weeks
- Population
- Pregnant women of white ethnicity from the Maternal Vitamin D Osteoporosis Study with genotype data and 25(OH)D at 14 and 34 weeks (analysed subset of the trial)
Response to Antenatal Cholecalciferol Supplementation Is Associated With Common Vitamin D-Related Genetic Variants.2017PMID:2857522410.1210/jc.2017-00682Industry fundedPermalink