Papers/PMID:28114352
Pharmacokinetic Evaluation of a Single Intramuscular High Dose versus an Oral Long-Term Supplementation of Cholecalciferol.
PloS one2017The record
1 finding · 1 compound · 1 endpoint
What it reported
How to read these marksWhat moved
1 finding
calciol — increases serum 25-hydroxyvitamin D concentration
Evidence strength: moderate.Findingreplicated ×33“On day 28, the 25(OH)D serum concentrations increased significantly and peaked in the vitamin D treated group with a mean of 70.9 nmol/l and remained low in the placebo treated individuals (mean 37.0 nmol/l, p = 0.002).”
Quoted verbatim from Pharmacokinetic Evaluation of a Single Intramuscular High Dose versus an Oral Long-Term Supplementation of Cholecalciferol.. - Study
- RCT
- Duration
- 4 weeks
- Dose
- single intramuscular injection of 100,000 IU cholecalciferol (D3-Vicotrat), against sodium chloride injection
- Population
- Healthy vitamin D deficient adults aged 18 to 60 in a randomised placebo-controlled pilot (2:1), Berlin winter months; day 28 timepoint, the peak, after a single intramuscular injection
Pharmacokinetic Evaluation of a Single Intramuscular High Dose versus an Oral Long-Term Supplementation of Cholecalciferol.2017PMID:2811435210.1371/journal.pone.0169620Industry fundedPermalink