Papers/PMID:27788688
High-dose intravenous selenium does not improve clinical outcomes in the critically ill: a systematic review and meta-analysis.
Critical care (London, England)2016The record
1 finding · 1 compound · 1 endpoint · 1 null
What it reported
How to read these marksEvery finding here is a null result.
What did not
1 finding
selenium atom — no detected effect on all-cause mortality
Evidence strength: moderate.FindingNull resultreplicated ×3“When the results of the 21 trials in which researchers reported mortality were aggregated, no statistically significant difference was found between Se supplementation and placebo (RR 0.98, 95 % CI 0.90–1.08, P = 0.72, heterogeneity I 2 = 0 %).”
Quoted verbatim from High-dose intravenous selenium does not improve clinical outcomes in the critically ill: a systematic review and meta-analysis.. - Study
- meta-analysis
- Population
- Critically ill adults in ICU, 21 RCTs of parenteral selenium as monotherapy or within antioxidant combinations versus placebo
Effect 0.98 risk ratio, 95% CI 0.9 to 1.08
High-dose intravenous selenium does not improve clinical outcomes in the critically ill: a systematic review and meta-analysis.2016PMID:2778868810.1186/s13054-016-1529-5An author is affiliated with a producerPermalink