Papers/PMID:27025786
Curcumin downregulates human tumor necrosis factor-α levels: A systematic review and meta-analysis ofrandomized controlled trials.
Pharmacological research2016The record
1 finding drawn from this paper, on 1 compound across 1 endpoint.
What it reported
How to read these marksWhat moved
1 finding
curcumin — decreases tumour necrosis factor alpha concentration
PreliminaryGrade D, Preliminary. Non-human or in vitro only.Findingreplicated ×2“There was a significant reduction of circulating TNF-α concentrations following curcumin supplementation (WMD: -4.69pg/mL, 95% CI: -7.10, -2.28, p<0.001).”
Quoted verbatim from Curcumin downregulates human tumor necrosis factor-α levels: A systematic review and meta-analysis ofrandomized controlled trials.. - Study
- meta-analysis
- Population
- adults across 8 RCTs of curcumin supplementation (disease population not specified in abstract)
Effect -4.69 mean difference, 95% CI -7.1 to -2.28
Curcumin downregulates human tumor necrosis factor-α levels: A systematic review and meta-analysis ofrandomized controlled trials.2016PMID:27025786