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PapersPMID:26607249

Effects of sodium nitrite supplementation on vascular function and related small metabolite signatures in middle-aged and older adults.

Journal of applied physiology (Bethesda, Md.2016The record ↗

  1. Finding, very limited evidenceraisesPlasma nitrite concentration

What moved

1 findingHow to read these marks →
  • “Ten weeks of sodium nitrite (80 or 160 mg/day, capsules, TheraVasc; randomized, placebo control, double blind) increased plasma nitrite acutely (5- to 15-fold, P < 0.001 vs. placebo) and chronically (P < 0.10) and was well tolerated without symptomatic hypotension or clinically relevant elevations in blood methemoglobin.”
    Study
    RCT
    Duration
    2 months
    Dose studied
    80 or 160 mg/day
    Population
    middle-aged and older adults

Study record

Design
randomised controlled trial
Species
human
Population
middle-aged and older adults
Participants
not reported
Comparator
placebo
Duration
70 days
Endpoints measured
10