PapersPMID:26607249
Effects of sodium nitrite supplementation on vascular function and related small metabolite signatures in middle-aged and older adults.
What moved
1 findingHow to read these marks →- Increases plasma nitrite concentration
very limited
“Ten weeks of sodium nitrite (80 or 160 mg/day, capsules, TheraVasc; randomized, placebo control, double blind) increased plasma nitrite acutely (5- to 15-fold, P < 0.001 vs. placebo) and chronically (P < 0.10) and was well tolerated without symptomatic hypotension or clinically relevant elevations in blood methemoglobin.”
- Study
- RCT
- Duration
- 2 months
- Dose studied
- 80 or 160 mg/day
- Population
- middle-aged and older adults
Study record
- Design
- randomised controlled trial
- Species
- human
- Population
- middle-aged and older adults
- Participants
- not reported
- Comparator
- placebo
- Duration
- 70 days
- Endpoints measured
- 10