Papers/PMID:26237622
Intraoperative Magnesium Administration Does Not Reduce Postoperative Atrial Fibrillation After Cardiac Surgery.
Anesthesia and analgesia2015The record
1 finding · 1 compound · 1 endpoint · 1 null
What it reported
How to read these marksEvery finding here is a null result.
What did not
1 finding
magnesium(2+) — no detected effect on postoperative atrial fibrillation incidence
Evidence strength: moderate.FindingNull resultreplicated ×1“There was no difference in the proportion of patients with new-onset POAF between the Mg group (42.5%, 95% confidence interval [CI], 35 – 50%)] and the placebo group (37.9%, 95% CI, 31 – 45%; p=0.40).”
Quoted verbatim from Intraoperative Magnesium Administration Does Not Reduce Postoperative Atrial Fibrillation After Cardiac Surgery.. - Study
- RCT
- Dose
- 50 mg/kg IV bolus over 20 min after induction of anesthesia, then 50 mg/kg infused over 3 h (total 100 mg/kg), versus saline placebo
- Population
- Adults undergoing CABG, valve, or CABG plus valve surgery with cardiopulmonary bypass, after excluding those with preoperative acute or chronic atrial fibrillation; intention-to-treat analysis
Intraoperative Magnesium Administration Does Not Reduce Postoperative Atrial Fibrillation After Cardiac Surgery.2015PMID:2623762210.1213/ANE.0000000000000873Permalink