Papers/PMID:24942646
Selenium supplementation in patients undergoing hematopoietic stem cell transplantation: effects on pro-inflammatory cytokines levels.
Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences2014The record
2 findings · 1 compound · 2 endpoints · 2 null
What it reported
How to read these marksEvery finding here is a null result.
What did not
2 findings
selenium atom — no detected effect on tumour necrosis factor alpha concentration
Evidence strength: moderate.FindingNull result“The mean plasma levels of TNF-α, IL-1β, and IL-6 were not significantly different between study groups at any sampling time point.”
Quoted verbatim from Selenium supplementation in patients undergoing hematopoietic stem cell transplantation: effects on pro-inflammatory cytokines levels.. - Study
- RCT
- Dose
- Se tablets 200 mcg, two tablets daily at 12-hour interval, from first day of high-dose chemotherapy through 14 days after transplant
- Population
- Adult patients with AML or ALL undergoing allogeneic hematopoietic stem cell transplantation after busulfan and cyclophosphamide, selenium vs placebo; plasma ELISA at baseline, day 7 and day 14 after transplant
Selenium supplementation in patients undergoing hematopoietic stem cell transplantation: effects on pro-inflammatory cytokines levels.2014PMID:2494264610.1186/2008-2231-22-51Permalink
selenium atom — no detected effect on interleukin-6 concentration
Evidence strength: limited.FindingNull result“The mean plasma levels of TNF-α, IL-1β, and IL-6 were not significantly different between study groups at any sampling time point.”
Quoted verbatim from Selenium supplementation in patients undergoing hematopoietic stem cell transplantation: effects on pro-inflammatory cytokines levels.. - Study
- RCT
- Dose
- Se tablets 200 mcg, two tablets daily at 12-hour interval, from first day of high-dose chemotherapy through 14 days after transplant
- Population
- Adult patients with AML or ALL undergoing allogeneic hematopoietic stem cell transplantation after busulfan and cyclophosphamide, selenium vs placebo; plasma ELISA at baseline, day 7 and day 14 after transplant
Selenium supplementation in patients undergoing hematopoietic stem cell transplantation: effects on pro-inflammatory cytokines levels.2014PMID:2494264610.1186/2008-2231-22-51Permalink